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SCHEMBL10031571

SCHEMBL10031571

C=C(C)C(=O)Nc1cccc(S(=O)(=O)Nc2nc(C)cc(C)n2)c1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.58
▸ PCTP Q9UKL6 2/20 0.57
▸ STARD10 Q9Y365 2/20 0.57
▸ TSHR P16473 2/20 0.56
▸ ALDH1A1 P00352 3/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49
▸ PKM P14618 1/20 0.49
▸ TDP1 Q9NUW8 2/20 0.49
▸ GAA P10253 2/20 0.48
▸ POLB P06746 1/20 0.47
▸ THRB P10828 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1688047 0.88 LMNA (0.67) LMNATSHRALDH1A1NPSR1TDP1
SCHEMBL396170 0.82 TDP1 (0.56) LMNAALDH1A1PKMTDP1GAA
SCHEMBL393893 0.79 TDP1 (0.59) LMNAALDH1A1PKMTDP1GAA
SCHEMBL393848 0.79 TDP1 (0.55) LMNATSHRALDH1A1PKMTDP1
SCHEMBL397572 0.79 AKR1C3 (0.59) LMNAALDH1A1PKMTDP1GAA
SCHEMBL396604 0.78 KMT2A (0.58) LMNAALDH1A1NPSR1PKMTDP1
SCHEMBL10031572 0.78 LMNA (0.48) LMNATSHRALDH1A1NPSR1GAA
SCHEMBL7597973 0.78 TDP1 (0.64) LMNAALDH1A1PKMTDP1GAA
SCHEMBL11842413 0.77 TDP1 (0.56) LMNAALDH1A1PKMTDP1SMN1; SMN2
SCHEMBL27404350 0.77 TDP1 (0.56) LMNAALDH1A1PKMTDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190176459-A1 POSITIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-06-13 — — US disclosed
US-8993216-B2 Method of producing a planographic printing plate FUJIFILM CORPORATION (JP) 2015-03-31 — — US disclosed
US-8993216-B2 Method of producing a planographic printing plate FUJIFILM CORPORATION (JP) 2015-03-31 — — US disclosed
EP-2106907-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-10-16 — — EP disclosed
US-20130260317-A1 METHOD OF PRODUCING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-10-03 — — US disclosed
US-20130260317-A1 METHOD OF PRODUCING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-10-03 — — US disclosed
US-8304166-B2 Heat sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-11-06 — — US disclosed
US-8110338-B2 Heat-sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-02-07 — — US disclosed
US-8110338-B2 Heat-sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-02-07 — — US disclosed
US-20100055610-A1 HEAT SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-03-04 — — US disclosed
EP-2159049-A1 A heat-sensitive positive-working lithographic printing plate precursor Agfa Graphics N.V. (BE) 2010-03-03 — — EP disclosed
US-20090253071-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-08 — — US disclosed
US-20090253071-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-08 — — US disclosed
US-20090170028-A1 HEAT-SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-07-02 — — US disclosed
US-20090170028-A1 HEAT-SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-07-02 — — US disclosed