⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15367193 | 0.69 | — | — | |
| SCHEMBL1767122 | 0.67 | — | — | |
| SCHEMBL3292879 | 0.67 | — | — | |
| SCHEMBL263643 | 0.67 | — | — | |
| SCHEMBL3288478 | 0.67 | — | — | |
| SCHEMBL2931955 | 0.67 | — | — | |
| SCHEMBL22756845 | 0.65 | — | — | |
| SCHEMBL721366 | 0.64 | — | — | |
| SCHEMBL821860 | 0.64 | — | — | |
| SCHEMBL16161246 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487080-B2 | Fluorine-labeled compounds | GENERAL ELECTRIC COMPANY (US) | 2013-07-16 | — | — | US | disclosed |
| US-8124725-B2 | PDGF-Rβ binders | GENERAL ELECTRIC COMPANY (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110160430-A1 | FLUORINE-LABELED COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2011-06-30 | — | — | US | disclosed |
| US-7902332-B2 | Reacting thiol-reactive terminus of linker with a polypeptide and fluorine-substituted aldehyde | GENERAL ELECTRIC COMPANY (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090191124-A1 | PDGF-RBeta BINDERS | GENERAL ELECTRIC COMPANY (US) | 2009-07-30 | — | — | US | disclosed |
| US-20080139787-A1 | Fluorine-labeled compounds | GENERAL ELECTRIC COMPANY | 2008-06-12 | — | — | US | disclosed |