Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | TSHR | P16473 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032159 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TSHRKMT2ASMN1; SMN2GAA | |
| SCHEMBL5073403 | 0.80 | DPP4 (0.79) | ALDH1A1TSHRKMT2ASMN1; SMN2GAA | |
| SCHEMBL4666981 | 0.73 | TSHR (0.72) | ALDH1A1TSHRKMT2AGAAMEN1 | |
| SCHEMBL4668769 | 0.71 | ALDH1A1 (0.59) | ALDH1A1TSHRKMT2ASMN1; SMN2GAA | |
| SCHEMBL4668663 | 0.70 | TSHR (0.73) | ALDH1A1TSHRKMT2AGAAMEN1 | |
| SCHEMBL22800988 | 0.69 | USP2 (0.67) | ALDH1A1TSHRKMT2ASMN1; SMN2GAA | |
| SCHEMBL13939659 | 0.69 | ALDH1A1 (0.80) | ALDH1A1TSHRKMT2ASMN1; SMN2GAA | |
| SCHEMBL1068145 | 0.69 | TSHR (0.64) | ALDH1A1TSHRKMT2ASMN1; SMN2GAA | |
| SCHEMBL555020 | 0.68 | DPP4 (1.00) | ALDH1A1TSHRKMT2AGAAMEN1 | |
| SCHEMBL4668968 | 0.68 | ALDH1A1 (0.56) | ALDH1A1TSHRKMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142682-A1 | ANTIVIRULENCE COMPOUNDS INHIBITING BACTERIAL MONO-ADP-RIBOSYLTRANSFERASE TOXINS | UNIVERSITY OF GUELPH (CA) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142682-A1 | ANTIVIRULENCE COMPOUNDS INHIBITING BACTERIAL MONO-ADP-RIBOSYLTRANSFERASE TOXINS | TIPARP, CD38, PARP14 | ALDH1A1 4539/4885TSHR 4217/4885KMT2A 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.