SCHEMBL1003218

SCHEMBL1003218

CCCCCCCNC(C)=O

nearest known ligand 0.80

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.80
MAPK1 P28482 1/20 0.80
HIF1A Q16665 1/20 0.80
EPHX1 P07099 10/20 0.70
PAOX Q6QHF9 3/20 0.68
CASP2 P42575 1/20 0.61
ADRA1A P35348 1/20 0.61
ZDHHC20 Q5W0Z9 1/20 0.57
ZDHHC2 Q9UIJ5 1/20 0.57
NAAA Q02083 1/20 0.57
FAAH O00519 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75904 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL2481694 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL1481880 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL14002535 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL8204709 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL25243376 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL7990903 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL559951 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL8979293 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL1457274 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108866352-A Process for producing lithium carbonate by extracting lithium in salt lake brine through phosphate ionic liquid 青海柴达木兴华锂盐有限公司 2018-11-23 CN claimed
CN-104946889-B A kind of method of extract and separate iron and aluminium from hydrochloric acid medium 广州绿华环保科技有限公司 2017-10-27 CN claimed
CN-104946889-A Method for extracting and separating iron and aluminum from hydrochloric acid media GUANGZHOU LYUHUA ENVIRONMENTAL PROT SCIENCE & TECHNOLOGY CO LTD 2015-09-30 CN claimed
WO-2008029278-A2 CONJUGATES OF ANTITHROMBIN BINDING OLIGOSACCHARIDE DERIVATIVES AND THERAPEUTIC PROTEINS ENDOTIS PHARMA S.A. (FR) 2008-03-13 WO claimed
EP-1886696-A1 Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins Endotis Pharma (FR) 2008-02-13 EP claimed
CN-1169791-C Novel acetamide derivatives and protease inhibitors �ձ���ҩ��ʽ���� 2004-10-06 CN claimed
CN-1229405-A Novel acetamide derivatives and protease inhibitors NIPPON KAYAKU KK (JP) 1999-09-22 CN claimed
CN-1033520-C Solvent extraction method concentration process of gibberellin fermented filtrate UNIV QINGHUA (CN) 1996-12-11 CN claimed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE LOXO ONCOLOGY, INC. 2024-01-18 US disclosed
WO-2023242661-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 WO disclosed
US-11826430-B2 Anti-cancer nuclear hormone receptor-targeting compounds NUVATION BIO INC. (US) 2023-11-28 US disclosed
US-20230241224-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE SANEGENE BIO USA INC. 2023-08-03 US disclosed
CN-1043319-A New amine and uses thereof MITSUI PHARMACEUTICALS (JP) 1990-06-27 CN disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed
US-4089865-A Certain thiazole compounds SYNTEX (U.S.A.) INC. (US) 1978-05-16 US disclosed
US-4001421-A THIAZOLE CARDIOVASCULAR AGENTS SYNTEX (U.S.A.) INC. (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PIK3CA, PIK3R4, PIK3R5 KDM4E 2656/4885MAPK1 148/4885HIF1A 4148/4885
US-20230241224-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE PARP1, PARP2, CD38 KDM4E 3319/4885MAPK1 3770/4885HIF1A 1722/4885
US-11826430-B2 Anti-cancer nuclear hormone receptor-targeting compounds NCOA1, NCOR1, NCOA3 KDM4E 1808/4885MAPK1 3381/4885HIF1A 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.