SCHEMBL1481880

SCHEMBL1481880

CCCCCCCCNC(C)=O

nearest known ligand 0.80

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.80
MAPK1 P28482 1/20 0.80
HIF1A Q16665 1/20 0.80
EPHX1 P07099 10/20 0.70
PAOX Q6QHF9 3/20 0.68
CASP2 P42575 1/20 0.61
ADRA1A P35348 1/20 0.61
ZDHHC20 Q5W0Z9 1/20 0.57
ZDHHC2 Q9UIJ5 1/20 0.57
NAAA Q02083 1/20 0.57
FAAH O00519 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003218 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL75904 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL2481694 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL14002535 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL8204709 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL25243376 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL7990903 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL559951 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL8979293 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX
SCHEMBL1457274 1.00 KDM4E (0.80) KDM4EMAPK1HIF1AEPHX1PAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116408203-A Method for separating feldspar from photovoltaic glass quartz sand by lepidolite tailings 合肥万泉非金属矿科技有限公司 2023-07-11 CN claimed
CN-109628758-A A kind of extractant and its extracting process of elemental lithium 虔东稀土集团股份有限公司 2019-04-16 CN claimed
CN-105837939-A Composite antibacterial plastic for refrigerator and preparation method of composite antibacterial plastic 宁波高新区夏远科技有限公司 2016-08-10 CN claimed
CN-101376929-A Method for extracting bismuth from bismuth ore concentrate or material containing bismuth UNIV CENTRAL SOUTH (CN) 2009-03-04 CN claimed
EP-1042355-A1 11BETA-HALOGEN-7ALPHA-SUBSTITUTED ESTRATRIENES, METHOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11BETA-HALOGEN-7ALPHA-SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS Schering Aktiengesellschaft (DE) 2000-10-11 EP claimed
WO-1999033855-A1 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES, METHOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-08 WO claimed
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE LOXO ONCOLOGY, INC. 2024-01-18 US disclosed
WO-2024009541-A1 METHOD FOR PRODUCING WATER-ABSORBING RESIN COMPOSITION SDPグローバル株式会社 2024-01-11 WO disclosed
US-11752086-B2 Topical formulations and methods MYOCEPT INC. (US) 2023-09-12 US disclosed
CN-116408203-A Method for separating feldspar from photovoltaic glass quartz sand by lepidolite tailings 合肥万泉非金属矿科技有限公司 2023-07-11 CN disclosed
WO-2023114937-A2 FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2023-06-22 WO disclosed
WO-2023091985-A1 COMPOUNDS TARGETING PMP22 FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH DISEASE DTX PHARMA, INC. (US) 2023-05-25 WO disclosed
US-20230162883-A1 COMPOSITION AND METHOD UNIV LIVERPOOL (GB) 2023-05-25 US disclosed
EP-0455206-A1 Compositions of liquid hydrocarbons originating from refining processes and showing improved low temperature properties SOCIETA' ITALIANA ADDITIVI PER CARBURANTI S.r.l. (IT) 1991-11-06 EP disclosed
US-4957917-A Anti-inflammatory furanones ALLERGAN, INC. (US) 1990-09-18 US disclosed
EP-0369813-A2 Anti-inflammatory furanones ALLERGAN, INC (US) 1990-05-23 EP disclosed
EP-0036560-B1 FOAMABLE OLEFIN POLYMER COMPOSITIONS STABILIZED WITH N-ALKYL SUBSTITUTED AMIDES, FOAMING PROCESS USING THEM AND FOAM ARTICLE PRODUCED THE DOW CHEMICAL COMPANY (US) 1985-03-27 EP disclosed
US-4345041-A Foaming synthetic resin compositions stabilized with N-(higher alkyl) C.sub. -C8 amides ASAHI-DOW LIMITED (JP) 1982-08-17 US disclosed
EP-0036560-A2 Foamable olefin polymer compositions stabilized with N-alkyl substituted amides, foaming process using them and foam article produced THE DOW CHEMICAL COMPANY (US) 1981-09-30 EP disclosed
US-4251655-A GASTRIC ACID ANTISECRETORY AGENTS MCNEILAB, INC. (US) 1981-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PIK3CA, PIK3R4, PIK3R5 KDM4E 2656/4885MAPK1 148/4885HIF1A 4148/4885
US-11752086-B2 Topical formulations and methods KRT18, ANXA3, VIP KDM4E 4065/4885MAPK1 4211/4885HIF1A 3689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.