SCHEMBL10032484

SCHEMBL10032484

Cc1cccc(-c2ccc(-c3cccc(-c4c5ccccc5c(-c5ccc6ccccc6c5)c5ccccc45)c3)cc2)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
CCR1 P32246 1/20 0.41
CCR8 P51685 1/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
IKBKB O14920 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
TGFBR1 P36897 2/20 0.38
CTRC Q99895 1/20 0.37
MEN1 O00255 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
RAC1 P63000 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032750 0.96 CYP2A6 (0.40) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032424 0.96 CYP2A6 (0.42) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032871 0.94 CCR1 (0.43) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL15977546 0.93 CCR1 (0.40) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032678 0.93 CYP2A6 (0.42) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032663 0.93 CCR1 (0.44) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032903 0.92 CYP2A6 (0.41) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032497 0.92 CCR1 (0.44) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032687 0.90 CYP2A6 (0.42) CYP2A6CCR1CCR8HSD17B1HSD17B2
SCHEMBL10032922 0.89 CYP2A6 (0.41) CYP2A6CCR1CCR8HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed