SCHEMBL10032663

SCHEMBL10032663

Cc1cccc(-c2ccc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4ccccc34)cc2)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.44
CCR8 P51685 1/20 0.44
IKBKB O14920 1/20 0.42
CYP2A6 P11509 1/20 0.41
TGFBR1 P36897 2/20 0.40
CTRC Q99895 1/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
RAC1 P63000 2/20 0.39
ACP1 P24666 1/20 0.38
CYP1A2 P05177 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11954043 0.94 CCR1 (0.44) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL10032484 0.93 CYP2A6 (0.41) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL18174599 0.93 CCR1 (0.41) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL10032871 0.93 CCR1 (0.43) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL15977546 0.92 CCR1 (0.40) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL10032750 0.92 CYP2A6 (0.40) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL15977569 0.91 CCR1 (0.42) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL10032424 0.91 CYP2A6 (0.42) CCR1CCR8IKBKBCYP2A6TGFBR1
SCHEMBL10032678 0.91 CYP2A6 (0.42) CCR1CCR8CYP2A6TGFBR1CYP1A1
SCHEMBL10032902 0.91 CCR1 (0.44) CCR1CCR8CYP2A6TGFBR1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed