SCHEMBL10032665

SCHEMBL10032665

Cc1ccc2ccc(-c3c4ccccc4c(-c4ccc(-c5cccc(-c6cccnc6)n5)cc4)c4ccccc34)cc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.48
CYP17A1 P05093 4/20 0.46
CYP19A1 P11511 3/20 0.46
CYP11B2 P19099 3/20 0.46
CYP11B1 P15538 2/20 0.46
KARS1 Q15046 1/20 0.46
ABL1 P00519 1/20 0.43
BCR P11274 1/20 0.43
CYP3A4 P08684 2/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
LMNA P02545 2/20 0.41
DHODH Q02127 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.40
MAP2K4 P45985 1/20 0.40
CYP2C9 P11712 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
HSD17B1 P14061 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032453 0.94 CYP2A6 (0.49) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1
SCHEMBL10032178 0.92 CYP2A6 (0.49) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1
SCHEMBL13015625 0.89 CYP11B1 (0.59) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1
SCHEMBL10032639 0.89 CYP11B2 (0.55) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1
SCHEMBL10032675 0.89 CYP11B2 (0.55) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1
SCHEMBL10032666 0.88 MAPT (0.45) CYP2A6CYP3A4LMNADHODHKDM4E
SCHEMBL10032867 0.88 CYP11B2 (0.57) CYP17A1CYP19A1CYP11B2CYP11B1ABL1
SCHEMBL10032648 0.86 CYP2A6 (0.52) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1
SCHEMBL10032669 0.85 CYP11B2 (0.51) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1
SCHEMBL10032907 0.85 CYP2A6 (0.51) CYP2A6CYP17A1CYP19A1CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed