Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032884 | 0.96 | GRM5 (0.43) | GRM5IRAK4SIRT2PKMTP53 | |
| SCHEMBL10032471 | 0.92 | GRM5 (0.44) | GRM5IRAK4SIRT2PKMTP53 | |
| SCHEMBL10032672 | 0.92 | DHODH (0.41) | GRM5IRAK4PKMTP53KDM4E | |
| SCHEMBL10032878 | 0.91 | IRAK4 (0.40) | GRM5IRAK4SIRT2PKMTP53 | |
| SCHEMBL10032873 | 0.88 | GRM5 (0.39) | GRM5IRAK4PKMTP53KDM4E | |
| SCHEMBL14506014 | 0.86 | SMN1; SMN2 (0.45) | GRM5IRAK4SIRT2PKMTP53 | |
| SCHEMBL10032650 | 0.85 | DHODH (0.41) | GRM5IRAK4PKMTP53KDM4E | |
| SCHEMBL10032893 | 0.85 | CYP2A6 (0.43) | SIRT2KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10032181 | 0.85 | GRM5 (0.44) | GRM5IRAK4LMNAMAPTNPSR1 | |
| SCHEMBL10032676 | 0.85 | MAPK14 (0.44) | SIRT2KDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060374-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | JNC株式会社 (JP) | 2012-05-10 | — | — | WO | disclosed |