Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032712 | 0.94 | DHODH (0.49) | DHODHABL1MKNK1MKNK2PTGS1 | |
| SCHEMBL10032759 | 0.93 | DHODH (0.48) | DHODHABL1MKNK1MKNK2CYP17A1 | |
| SCHEMBL10032694 | 0.90 | DHODH (0.48) | DHODHABL1MKNK1MKNK2PTGS1 | |
| SCHEMBL15977587 | 0.90 | DHODH (0.46) | DHODHABL1MKNK1MKNK2CYP17A1 | |
| SCHEMBL15161075 | 0.89 | DHODH (0.49) | DHODHABL1MKNK1MKNK2TOP1 | |
| SCHEMBL15977672 | 0.89 | DHODH (0.49) | DHODHABL1MKNK1MKNK2TOP1 | |
| SCHEMBL15160993 | 0.88 | DHODH (0.46) | DHODHABL1MKNK1MKNK2CYP17A1 | |
| SCHEMBL18174607 | 0.86 | DHODH (0.47) | DHODHABL1MKNK1MKNK2TOP1 | |
| SCHEMBL10032656 | 0.86 | DHODH (0.43) | DHODHABL1CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL16189088 | 0.85 | MKNK1 (0.54) | DHODHMKNK1MKNK2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060374-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME | JNC株式会社 (JP) | 2012-05-10 | — | — | WO | disclosed |