SCHEMBL15977672

SCHEMBL15977672

Cc1ncccc1-c1ccc(-c2ccc3c(-c4ccccc4)c4ccccc4c(-c4ccccc4)c3c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 5/20 0.49
MKNK1 Q9BUB5 1/20 0.44
MKNK2 Q9HBH9 1/20 0.44
PRMT5 O14744 1/20 0.43
WDR77 Q9BQA1 1/20 0.43
PIK3CA P42336 1/20 0.40
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
METAP2 P50579 1/20 0.38
TDO2 P48775 1/20 0.38
TOP1 P11387 2/20 0.37
IMPDH2 P12268 1/20 0.37
CKS1B P61024 2/20 0.36
SKP2 Q13309 2/20 0.36
GLO1 Q04760 1/20 0.36
ACVR1 Q04771 1/20 0.36
ABL1 P00519 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161075 1.00 DHODH (0.49) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL18174607 0.97 DHODH (0.47) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL18174614 0.94 DHODH (0.49) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL10300940 0.94 DHODH (0.48) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL15160994 0.92 DHODH (0.44) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL10032685 0.89 DHODH (0.50) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL16189088 0.88 MKNK1 (0.54) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL15160993 0.88 DHODH (0.46) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL15977587 0.87 DHODH (0.46) DHODHMKNK1MKNK2PRMT5WDR77
SCHEMBL18174670 0.84 DHODH (0.45) DHODHMKNK1MKNK2TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed