SCHEMBL10032689

SCHEMBL10032689

Cc1cccc(-c2ccc3ccc(-c4c5ccccc5c(-c5ccccc5)c5ccccc45)cc3c2)n1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.43
CCR8 P51685 1/20 0.43
CYP2A6 P11509 1/20 0.43
TGFBR1 P36897 5/20 0.40
MEN1 O00255 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
IRAK4 Q9NWZ3 2/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032922 0.97 CYP2A6 (0.41) CCR1CCR8CYP2A6TGFBR1MEN1
SCHEMBL10032902 0.95 CCR1 (0.44) CCR1CCR8CYP2A6TGFBR1MEN1
SCHEMBL10032903 0.94 CYP2A6 (0.41) CCR1CCR8CYP2A6TGFBR1MEN1
SCHEMBL10032687 0.93 CYP2A6 (0.42) CCR1CCR8CYP2A6TGFBR1MEN1
SCHEMBL10032871 0.91 CCR1 (0.43) CCR1CCR8CYP2A6TGFBR1RAB9A
SCHEMBL10032750 0.90 CYP2A6 (0.40) CCR1CCR8CYP2A6TGFBR1CYP1A1
SCHEMBL10032678 0.90 CYP2A6 (0.42) CCR1CCR8CYP2A6TGFBR1MEN1
SCHEMBL10032424 0.90 CYP2A6 (0.42) CCR1CCR8CYP2A6TGFBR1RAB9A
SCHEMBL10032663 0.90 CCR1 (0.44) CCR1CCR8CYP2A6TGFBR1CYP1A1
SCHEMBL17532878 0.89 CCR1 (0.47) CCR1CCR8CYP2A6TGFBR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012060374-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC株式会社 (JP) 2012-05-10 WO disclosed