SCHEMBL100327

SCHEMBL100327

C[CH]CCCCCCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.53
FAAH O00519 2/20 0.48
TRPV1 Q8NER1 1/20 0.48
DNM1 Q05193 3/20 0.47
EP300 Q09472 1/20 0.42
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2190769 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL5394503 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL200765 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL104031 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL199975 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL32612 1.00
SCHEMBL5403985 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL20495965 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL20495962 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL100650 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024071045-A1 POLYCARBONATE RESIN AND MOLDED ARTICLE CONTAINING SAME 富士フイルム株式会社 2024-04-04 WO disclosed
CN-112638977-B Polyisocyanate composition, polyurethane foam obtained therefrom and use thereof 巴斯夫欧洲公司 2024-03-19 CN disclosed
CN-112823149-B Carboxylic acid type lipid, lipid particle and lipid membrane containing the same 东丽株式会社 2024-03-08 CN disclosed
WO-2024018762-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2024018761-A1 NEUTRAL LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 EP disclosed
WO-2023078950-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed
WO-2023078946-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed
WO-2023078954-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed
CN-116019960-A Hemostatic material 东丽株式会社 2023-04-28 CN disclosed
WO-2002098532-A1 DEFOAMING AGENT AND/OR DEAERATING AGENT BASED ON OIL-IN-WATER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2002-12-12 WO disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed
EP-0305114-A1 Heat treating oil NIPPON OIL CO. LTD. (JP) 1989-03-01 EP disclosed
US-4605645-A ANTITUMOR AGENTS TEIJIN LIMITED (JP) 1986-08-12 US disclosed
EP-0081386-B1 5-FLUORO-2'-DEOXYURIDINE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF TEIJIN LIMITED (JP) 1985-05-29 EP disclosed
US-4431703-A POLYSILOXANE AND SILOXANE LUBRICANTS; AMID DEVICES; TELEVISION; MAGNETIC TAPES SONY CORPORATION (JP) 1984-02-14 US disclosed
EP-0081386-A1 5-Fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof TEIJIN LIMITED (JP) 1983-06-15 EP disclosed
US-4369230-A POLYSILOXANE LUBRICANTS SONY CORPORATION (JP) 1983-01-18 US disclosed