SCHEMBL2190769

SCHEMBL2190769

C[CH]CCCCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.53
FAAH O00519 2/20 0.48
TRPV1 Q8NER1 1/20 0.48
DNM1 Q05193 3/20 0.47
EP300 Q09472 1/20 0.42
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5394503 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL200765 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL104031 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL199975 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL32612 1.00
SCHEMBL5403985 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL100327 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL20495965 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL20495962 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL100650 1.00 TSHR (0.55) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181763-B1 Catalyst and process for alkoxylation SHELL INT RESEARCH (NL) 2012-06-20 EP claimed
EP-2181763-A1 Catalyst and process for alkoxylation Shell Internationale Research Maatschappij B.V. (NL) 2010-05-05 EP claimed
WO-2023078954-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed
WO-2023078946-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed
WO-2023078950-A1 LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY ZIPHIUS VACCINES NV (BE) 2023-05-11 WO disclosed
EP-3919464-A1 CURING AGENT, METHOD FOR PRODUCING CEMENT STRUCTURE WITH COATING FILM, SHRINKAGE REDUCTION METHOD AND DRYING SUPPRESSION METHOD FOR CEMENT MOLDED BODY, AND METHOD FOR SUPPRESSING PENETRATION OF DETERIORATION FACTOR INTO CEMENT STRUCTURE Nippon Shokubai Co., Ltd. (JP) 2021-12-08 EP disclosed
US-10766774-B2 Oxidized graphite derivative and method for producing same NIPPON SHOKUBAI CO., LTD. (JP) 2020-09-08 US disclosed
WO-2020071563-A1 ALKYLENE GLYCOL DERIVATIVE, ADDITIVE FOR DETERGENTS, AND DETERGENT COMPOSITION 株式会社日本触媒 2020-04-09 WO disclosed
US-20180327269-A1 OXIDIZED GRAPHITE DERIVATIVE AND METHOD FOR PRODUCING SAME NIPPON SHOKUBAI CO., LTD. (JP) 2018-11-15 US disclosed
EP-3375756-A1 OXIDIZED GRAPHITE DERIVATIVE AND METHOD FOR PRODUCING SAME Nippon Shokubai Co., Ltd. (JP) 2018-09-19 EP disclosed
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
US-7183325-B2 Deforming agent and/or deaerating agent based on oil-in-water dispersions BASF AKTIENGESELLSCHAFT (DE) 2007-02-27 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2005-10-20 US disclosed
EP-1397188-B1 DEFOAMING AGENT AND/OR DEAERATING AGENT BASED ON OIL-IN-WATER DISPERSIONS BASF AG (DE) 2005-09-14 EP disclosed
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed
US-20040176480-A1 Defoaming agent and/or deaerating agent based on oil-in-water dispersions BASF AKTIENGESELLSCHAFT (DE) 2004-09-09 US disclosed
EP-1397188-A1 DEFOAMING AGENT AND/OR DEAERATING AGENT BASED ON OIL-IN-WATER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2004-03-17 EP disclosed
WO-2002098532-A1 DEFOAMING AGENT AND/OR DEAERATING AGENT BASED ON OIL-IN-WATER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 TSHR 1087/4885THRB 1170/4885FAAH 2114/4885
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether NOX4, CBR1, CBR3 TSHR 1685/4885THRB 2315/4885FAAH 3637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.