SCHEMBL10033079

SCHEMBL10033079

C=CC(=O)OCCC(CCC)SC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
HPGD P15428 1/20 0.53
ALDH1A1 P00352 4/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 3/20 0.41
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATM Q13315 1/20 0.35
HCAR2 Q8TDS4 4/20 0.33
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2732425 0.88 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL111396 0.79 ALDH1A1 (0.47) TSHRALDH1A1CYP3A4HSD17B10SMN1; SMN2
SCHEMBL641953 0.77 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27821518 0.77 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27800523 0.77 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1899131 0.77 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28343377 0.76 TSHR (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4373216 0.76 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
Ammonia Solution, Strong SCHEMBL22686891 0.76
Propane SCHEMBL6904776 0.75 TSHR (0.73) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124194-B2 Ink composition comprising a compound with a sulfide bond and an ink jet recording method FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-8124194-B2 Ink composition comprising a compound with a sulfide bond and an ink jet recording method FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090136678-A1 Ink composition and ink jet recording method FUJIFILM CORPORATION (JP) 2009-05-28 US disclosed
US-20090136678-A1 Ink composition and ink jet recording method FUJIFILM CORPORATION (JP) 2009-05-28 US disclosed