SCHEMBL10033083

SCHEMBL10033083

C=CC(=O)OCCCSCCCC

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.72
HPGD P15428 1/20 0.72
ALDH1A1 P00352 4/20 0.57
CYP3A4 P08684 1/20 0.57
ATM Q13315 1/20 0.50
TP53 P04637 2/20 0.47
HIF1A Q16665 2/20 0.47
HSD17B10 Q99714 1/20 0.47
HCAR2 Q8TDS4 3/20 0.44
THRB P10828 3/20 0.44
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PLA2G4B P0C869 1/20 0.38
THRA P10827 1/20 0.37
CES1 P23141 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17416309 0.93 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL10033081 0.93 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL22861291 0.91 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL4887765 0.87 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL6086010 0.86 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL22710146 0.86 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL6408701 0.86 TSHR (0.62) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL28541902 0.85 TSHR (0.72) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1331857 0.85
SCHEMBL5681395 0.85 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124194-B2 Ink composition comprising a compound with a sulfide bond and an ink jet recording method FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-8124194-B2 Ink composition comprising a compound with a sulfide bond and an ink jet recording method FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090136678-A1 Ink composition and ink jet recording method FUJIFILM CORPORATION (JP) 2009-05-28 US disclosed
US-20090136678-A1 Ink composition and ink jet recording method FUJIFILM CORPORATION (JP) 2009-05-28 US disclosed