Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408701 | 1.00 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL22710146 | 1.00 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL17416309 | 0.93 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL10033081 | 0.93 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL10426942 | 0.89 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL9860378 | 0.89 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL31493314 | 0.87 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL15994380 | 0.87 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL15994950 | 0.87 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL30998835 | 0.87 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074937-B2 | Method for production of additives for lubricating oils | ROHM AND HAAS COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1361217-B1 | 4-Thionoimidazolidine derivatives as oil-soluble additives for lubricating oils | ROHM & HAAS (US) | 2005-03-23 | — | — | EP | disclosed |
| US-6734149-B2 | THIOHYDANTOIN DERIVATIVE, DITHIOPHOSPHATE | ROHM AND HAAS COMPANY | 2004-05-11 | — | — | US | disclosed |
| US-20040082797-A1 | Method for production of additives for lubricating oils | ROHM AND HAAS COMPANY | 2004-04-29 | — | — | US | disclosed |
| EP-1413577-A1 | Process for production of additives for lubricating oils | Rohm and Haas (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-1361217-A1 | 4-Thionoimidazolidine derivatives as oil-soluble additives for lubricating oils | ROHM AND HAAS COMPANY (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-1229023-B1 | Thioimidazolidine derivatives as oil-soluble additives for lubricating oils | ROHM & HAAS (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6602831-B2 | Ashless, phosphorus-free; compounds contain a thio- or thiono-substituted imidazole or imidazoline ring | ROHM AND HAAS COMPANY | 2003-08-05 | — | — | US | disclosed |
| US-20020198115-A1 | Combination of additives for lubricating oils | ROHM AND HAAS COMPANY | 2002-12-26 | — | — | US | disclosed |
| US-20020142921-A1 | Oil-soluble additives for lubricating oils | ROHM AND HAAS COMPANY | 2002-10-03 | — | — | US | disclosed |
| EP-1229023-A1 | Thioimidazolidine derivatives as oil-soluble additives for lubricating oils | ROHM AND HAAS COMPANY (US) | 2002-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082797-A1 | Method for production of additives for lubricating oils | OR10J3, KAT7, NAA10 | TSHR 729/4885HPGD 3545/4885ALDH1A1 2276/4885 |
| US-20020198115-A1 | Combination of additives for lubricating oils | DAGLA, SAAL1, DAGLB | TSHR 4725/4885HPGD 3262/4885ALDH1A1 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.