Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.61 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.54 |
| ▸ | RRM1 | P23921 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085598 | 1.00 | GNAI3 (0.61) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL10033855 | 0.90 | GNAI3 (0.59) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL12085595 | 0.90 | GNAI3 (0.59) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL10033839 | 0.90 | GNAI3 (0.62) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL12085567 | 0.90 | GNAI3 (0.62) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL24179776 | 0.90 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL12085475 | 0.90 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL10033848 | 0.90 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5965246 | 0.88 | GNAI3 (0.71) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5965329 | 0.88 | GNAI3 (0.71) | GNAI3GNAO1GNAI1DPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |