Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.83 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.83 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.83 |
| ▸ | RRM1 | P23921 | 1/20 | 0.73 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.70 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 5/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407777 | 1.00 | GNAI3 (0.83) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL19402067 | 1.00 | GNAI3 (0.83) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL19407832 | 1.00 | GNAI3 (0.83) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL12085596 | 1.00 | GNAI3 (0.83) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL12085594 | 1.00 | GNAI3 (0.83) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL10033861 | 1.00 | GNAI3 (0.83) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL22646980 | 0.99 | GNAI3 (0.86) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL12085597 | 0.96 | GNAI3 (0.76) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL10033856 | 0.96 | GNAI3 (0.76) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL14048412 | 0.94 | DPP7 (0.73) | GNAI3GNAO1GNAI1RRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |