SCHEMBL10034053

SCHEMBL10034053

Cc1cn([C@H]2CC(OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)CC3O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.68
▸ F2 P00734 2/20 0.56
▸ TERT O14746 2/20 0.55
▸ POLB P06746 2/20 0.54
▸ ENPP1 P22413 3/20 0.54
▸ P2RY1 P47900 1/20 0.54
▸ TK1 P04183 1/20 0.48
▸ TYMS P04818 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19069603 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL19069699 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL16743928 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL16508423 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL20090644 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL20090645 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL23476999 0.94 F2 (0.63) DTYMKF2TERTPOLBENPP1
SCHEMBL8612856 0.93 DTYMK (0.74) DTYMKF2TERTPOLBENPP1
SCHEMBL8613042 0.93 DTYMK (0.74) DTYMKF2TERTPOLBENPP1
SCHEMBL17268344 0.93 DTYMK (0.74) DTYMKF2TERTPOLBENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040234-B2 Oligonucleotide analogs as therapeutic agents SPRING BANK PHARMACEUTICALS, INC. (US) 2015-05-26 — — US disclosed
US-20120053226-A1 DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS SPRING BANK PHARMACEUTICALS, INC. (US) 2012-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053226-A1 DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS TLR3, TLR5, TLR9 DTYMK 22/4885F2 4766/4885TERT 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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