SCHEMBL16743928

SCHEMBL16743928

Cc1cn([C@H]2C[C@@H](OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@H]3O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.68
▸ F2 P00734 2/20 0.56
▸ TERT O14746 2/20 0.55
▸ POLB P06746 2/20 0.54
▸ ENPP1 P22413 3/20 0.54
▸ P2RY1 P47900 1/20 0.54
▸ TK1 P04183 1/20 0.48
▸ TYMS P04818 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19069603 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL19069699 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL10034053 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL16508423 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL20090644 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL20090645 1.00 DTYMK (0.68) DTYMKF2TERTPOLBENPP1
SCHEMBL23476999 0.94 F2 (0.63) DTYMKF2TERTPOLBENPP1
SCHEMBL8612856 0.93 DTYMK (0.74) DTYMKF2TERTPOLBENPP1
SCHEMBL8613042 0.93 DTYMK (0.74) DTYMKF2TERTPOLBENPP1
SCHEMBL17268344 0.93 DTYMK (0.74) DTYMKF2TERTPOLBENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040234-B2 Oligonucleotide analogs as therapeutic agents SPRING BANK PHARMACEUTICALS, INC. (US) 2015-05-26 — — US disclosed
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