Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19621 | 0.88 | — | — | |
| SCHEMBL229715 | 0.88 | ALDH1A1 (0.35) | ALDH1A1MEN1GMNNGABBR2LMNA | |
| SCHEMBL31588091 | 0.84 | — | — | |
| Bromide SCHEMBL8990184 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MEN1GMNNGABBR2LMNA | |
| SCHEMBL31172630 | 0.84 | — | — | |
| SCHEMBL9650455 | 0.84 | — | — | |
| SCHEMBL7650639 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MEN1GMNNGABBR2LMNA | |
| Bromide SCHEMBL8990185 | 0.84 | — | — | |
| SCHEMBL2277021 | 0.84 | — | — | |
| SCHEMBL28347473 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046059-A1 | PHARMACEUTICALLY ACCEPTABLE FORMULATIONS/COMPOSITIONS FOR PEPTIDYL DRUGS | ZELOS THERAPEUTICS, INC. (US) | 2011-02-24 | — | — | US | claimed |
| WO-2011011675-A1 | PHARMACEUTICALLY ACCEPTABLE FORMULATIONS/COMPOSITIONS FOR PEPTIDYL DRUGS | ZELOS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | claimed |
| US-20110046059-A1 | PHARMACEUTICALLY ACCEPTABLE FORMULATIONS/COMPOSITIONS FOR PEPTIDYL DRUGS | ZELOS THERAPEUTICS, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| WO-2011011675-A1 | PHARMACEUTICALLY ACCEPTABLE FORMULATIONS/COMPOSITIONS FOR PEPTIDYL DRUGS | ZELOS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |