Dibenzothiophene

Dibenzothiophene

SCHEMBL1003452

c1ccc2c(c1)sc1ccccc12.c1ccsc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.74
ALDH1A1 P00352 5/20 0.50
MAPT P10636 5/20 0.50
RAB9A P51151 3/20 0.50
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 2/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP1A2 P05177 1/20 0.37
MCL1 Q07820 1/20 0.36
IKBKB O14920 1/20 0.36
LIMK1 P53667 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzothiophene SCHEMBL13294 0.86 GPR3 (1.00) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL14659543 0.86 GPR3 (1.00) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL30167635 0.86 GPR3 (1.00) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL3101427 0.83 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL3101419 0.83 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL9934048 0.83 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL28979299 0.83 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL10943387 0.83 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL21121001 0.83 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL29696490 0.83 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863209-B2 Methods for recycling catalyst compositions for aromatic ring halogenation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-01-04 US claimed
CN-1968750-A Catalyst composition and its use in aromatic chlorination reactions GEN ELECTRIC (US) 2007-05-23 CN claimed
US-20050283033-A1 Catalyst compositions and their use for chlorinating aromatic compounds GENERAL ELECTRIC COMPANY 2005-12-22 US claimed
US-20050283034-A1 Methods for recycling catalyst compositions for aromatic ring halogenation GENERAL ELECTRIC COMPANY 2005-12-22 US claimed
CN-109824870-B Electroluminescent polymer based on dibenzothiophene sulfhydrate unit and preparation method and application thereof 东莞华工协同创新科技发展有限公司 2021-07-27 CN disclosed
CN-109824870-B Electroluminescent polymer based on dibenzothiophene sulfhydrate unit and preparation method and application thereof 东莞华工协同创新科技发展有限公司 2021-07-27 CN disclosed
CN-112088430-A Solid-state imaging element, solid-state imaging device, electronic apparatus, and method for manufacturing solid-state imaging element 索尼公司 2020-12-15 CN disclosed
CN-103936538-B Method for preparing phenol by performing catalytic oxidation on aryl boron compound 南京师范大学 2017-02-15 CN disclosed
US-7282615-B2 Catalyst compositions and their use for chlorinating aromatic compounds SABIC INNOVATIVE PLASTICS, IP BV 2007-10-16 US disclosed
CN-1968750-A Catalyst composition and its use in aromatic chlorination reactions GEN ELECTRIC (US) 2007-05-23 CN disclosed
WO-2006009678-A1 CATALYST COMPOSITIONS AND THEIR USE FOR CHLORINATING AROMATIC COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2006-01-26 WO disclosed
US-20050283033-A1 Catalyst compositions and their use for chlorinating aromatic compounds GENERAL ELECTRIC COMPANY 2005-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050283034-A1 Methods for recycling catalyst compositions for aromatic ring halogenation PRKACG, HCN4, CLIC4 GPR3 939/4885ALDH1A1 3335/4885MAPT 2228/4885
US-20050283033-A1 Catalyst compositions and their use for chlorinating aromatic compounds PRKACG, PRKACA, PRKACB GPR3 1430/4885ALDH1A1 3060/4885MAPT 4065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.