SCHEMBL10034722

SCHEMBL10034722

CC(C)(C)OC(=O)N1CCC(c2noc3c(Oc4ccc(S(C)(=O)=O)cc4F)ncnc23)CC1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.73
CYP2C9 P11712 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL905129 0.88 GPR119 (0.65) GPR119
SCHEMBL905128 0.85 GPR119 (1.00) GPR119CYP2C9
SCHEMBL905138 0.79 GPR119 (0.77) GPR119
SCHEMBL905118 0.78 GPR119 (0.88) GPR119CYP2C9
SCHEMBL355414 0.76 CYP3A4 (0.57) GPR119CYP2C9
SCHEMBL1128441 0.76 CYP3A4 (0.78) GPR119CYP2C9
SCHEMBL386447 0.75 GPR119 (0.56) GPR119CYP2C9
SCHEMBL905143 0.75 GPR119 (0.82) GPR119CYP2C9
SCHEMBL10139822 0.74 CYP3A4 (0.55) GPR119CYP2C9
SCHEMBL14875472 0.74 GPR119 (0.64) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012043505-A1 NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME 興和株式会社 (JP) 2012-04-05 WO disclosed