Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000828 | 1.00 | HDAC1 (0.65) | HDAC1 | |
| SCHEMBL1001086 | 0.83 | HDAC1 (0.64) | HDAC1 | |
| SCHEMBL1884523 | 0.81 | HDAC1 (0.73) | HDAC1 | |
| SCHEMBL1891537 | 0.79 | HDAC1 (0.74) | HDAC1 | |
| SCHEMBL1883963 | 0.79 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL1892719 | 0.79 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL1887639 | 0.79 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL1890974 | 0.79 | HDAC1 (0.73) | HDAC1 | |
| SCHEMBL1001467 | 0.78 | HDAC1 (0.68) | HDAC1 | |
| SCHEMBL4459748 | 0.78 | HDAC1 (0.68) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872024-B2 | Benzothiophene hydroxamic acid derivatives with carbamate, urea, amide and sulfonamide substitutions | MERCK SHARP & DOHME CORP. (US) | 2011-01-18 | — | — | US | claimed |
| US-7872024-B2 | Benzothiophene hydroxamic acid derivatives with carbamate, urea, amide and sulfonamide substitutions | MERCK SHARP & DOHME CORP. (US) | 2011-01-18 | — | — | US | disclosed |