SCHEMBL10035100

SCHEMBL10035100

CC(C)(C)OC(=O)NCCNc1cccc2c(S(=O)(=O)O)cccc12

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.48
CA12 O43570 6/20 0.44
CA9 Q16790 6/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
BCHE P06276 1/20 0.44
NQO2 P16083 1/20 0.44
CA1 P00915 7/20 0.42
CA2 P00918 7/20 0.42
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
BRD4 O60885 2/20 0.42
METAP2 P50579 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
LATS1 O95835 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14667071 0.89 MALT1 (0.47) MALT1CA12CA9CA4CA7
SCHEMBL22461476 0.84 NAMPT (0.46) BRD4
SCHEMBL22461371 0.84 CA7 (0.47) CA12CA9CA4CA7CA14
SCHEMBL14667072 0.83 MALT1 (0.43) MALT1CA12CA9CA4CA7
SCHEMBL6128009 0.83 CA12 (0.63) CA12CA9CA4CA7CA14
SCHEMBL1514682 0.82 BCHE (0.48) MALT1BCHE
SCHEMBL134374 0.82 CA12 (0.47) CA12CA9CA4CA7CA14
SCHEMBL12041802 0.82 TTR (0.44) CA12CA9CA4CA7CA14
SCHEMBL21347989 0.81 CA12 (0.47) CA12CA9CA4CA7CA14
SCHEMBL21347987 0.81 CA12 (0.47) CA12CA9CA4CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802710-B1 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES LUMINEX CORP (US) 2016-02-24 EP disclosed
EP-2559738-B1 Methods for forming dyed microspheres and populations of dyed microspheres LUMINEX CORP (US) 2014-07-09 EP disclosed
EP-2559738-A1 Methods for forming dyed microspheres and populations of dyed microspheres Luminex Corporation (US) 2013-02-20 EP disclosed
US-8361169-B2 Methods for forming dyed microspheres and populations of dyed microspheres LUMINEX CORPORATION (US) 2013-01-29 US disclosed
US-20120035328-A1 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES HOFFACKER KURT D (US) 2012-02-09 US disclosed
US-8038734-B2 Methods for forming dyed microspheres and populations of dyed microspheres LUMINEX CORPORATION (US) 2011-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035328-A1 METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES CD68, CD14, MYADM MALT1 4703/4885CA12 1450/4885CA9 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.