CD14 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1724181	0.61	7/20
SCHEMBL13987040	0.57	7/20
SCHEMBL13987039	0.51	7/20
SCHEMBL13987036	0.47	7/20
SCHEMBL14617492	0.57	6/20
SCHEMBL16545619	0.56	6/20
SCHEMBL1722335	0.55	6/20
SCHEMBL14617494	0.55	6/20
SCHEMBL14617493	0.52	6/20
SCHEMBL18863517	0.46	6/20
Trifluoroacetic Acid (SCHEMBL4965389)	0.52	5/20
SCHEMBL16545623	0.53	4/20
SCHEMBL16545626	0.53	4/20
SCHEMBL30388098	0.51	4/20
SCHEMBL6202528	0.48	4/20
SCHEMBL757636	0.43	4/20
SCHEMBL2184946	0.54	3/20
SCHEMBL2217463	0.54	3/20
SCHEMBL16545609	0.53	3/20
SCHEMBL16545620	0.52	3/20

Clinical trials — most relevant to CD14 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Exercise And Rosuvastatin Treatment: Is There an Anti-Inflammatory Synergy?	PHASE4	UNKNOWN
Effects of Hemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression	PHASE4	UNKNOWN
Effects of Raltegravir Based Regimen on Platelet Reactivity, Platelet-monocyte Aggregation and Immune Activation	PHASE4	COMPLETED
Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia	PHASE2	COMPLETED
Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease	PHASE2	COMPLETED
Salt-Sensitivity and Immunity Cell Activation	PHASE1/PHASE2	ACTIVE_NOT_RECRUITING
Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans	PHASE2	NOT_YET_RECRUITING
Clinical Trial of SBRT and Systemic Pembrolizumab With or Without Avelumab/Ipilimumab+ Dendritic Cells in Solid Tumors	PHASE2	UNKNOWN
The Effects of GLA on Human Volunteers	PHASE1	COMPLETED
Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1	nan	UNKNOWN
Postprandial Monocyte Study	nan	COMPLETED
Impact of Neutrophil Lymphocyte and Monocyte Lymphocyte Ratio on Chronic Kidney Disease Patients Outcome	nan	UNKNOWN
Fetal Programming of Immune Response and Body Fat by Maternal Obesity	nan	COMPLETED
Utility of Presepsin in Children Sepsis	nan	UNKNOWN
Immune Monitoring After Allogeneic Hematopoietic Stem Cell Transplantation	nan	COMPLETED
Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients	nan	COMPLETED
Fibrocytes in Early and Longstanding Rheumatoid Arthritis	nan	COMPLETED
Immunological Biomarkers in Patients With Acute Ischemic Stroke	nan	COMPLETED
Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response	nan	COMPLETED
Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis	nan	RECRUITING
Monocyte Soluble Activation Markers sCD14 and sCD163 in Children With Type 1 Diabetes Mellitus	nan	UNKNOWN
Toll-like Receptor 2 Gene Polymorphism, Serum Cytokines and Susceptibility to Disease Severity or Treatment Response of Pulmonary Tuberculosis	nan	COMPLETED
Myeloid Derived Suppressor Cells and Chronic Myeloid Leukemia	nan	UNKNOWN
Differences in Bone Cell Activity Between Rheumatoid Arthritis and Ankylosing Spondylitis	nan	COMPLETED
Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction	nan	COMPLETED
New Markers for Diagnosis of Prosthetic Infections	nan	UNKNOWN
Immunomodulatory Vitamin D in Thalassemia	nan	COMPLETED
Immunologic Markers for the Differential Diagnosis Between Uveitis-TBC and Uveitis-SARC (TBC-SARC)	nan	COMPLETED
Heterogeneity of Dendritic Cells in Colon and Non-small Cell Lung Cancer	nan	UNKNOWN
Myeloid Derived Suppressor Cells in Systemic Lupus Erythematosus	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a CD14 binder may also engage these)

Protein	Name	Similarity
Q63691	—	1.000	Q63691 →
Q28680	—	0.999	Q28680 →
P10810	—	0.997	P10810 →
Q95122	—	0.996	Q95122 →
Q6QNU9	—	0.988	Q6QNU9 →
Q9Y4C4	—	0.984	Q9Y4C4 →
Q86YC3	—	0.984	Q86YC3 →
Q3ZBI5	—	0.984	Q3ZBI5 →
Q8BMT4	—	0.984	Q8BMT4 →
Q6R5P0	—	0.984	Q6R5P0 →
Q96ME1	—	0.984	Q96ME1 →
Q8TBC3	—	0.984	Q8TBC3 →
P28986	—	0.984	P28986 →
P03173	—	0.983	P03173 →
Q89730	—	0.983	Q89730 →
Q7TQH7	—	0.983	Q7TQH7 →
Q5BIR3	—	0.982	Q5BIR3 →
Q9Y6U7	—	0.982	Q9Y6U7 →
A3KMV1	—	0.982	A3KMV1 →
P0CC10	—	0.982	P0CC10 →
Q9CZT5	—	0.982	Q9CZT5 →
O70513	—	0.982	O70513 →
A4QNX3	—	0.982	A4QNX3 →
P06475	—	0.982	P06475 →
O08852	—	0.982	O08852 →
P04488	—	0.982	P04488 →
Q9BZC7	—	0.982	Q9BZC7 →
Q5SPX3	—	0.982	Q5SPX3 →
Q9UPV7	—	0.982	Q9UPV7 →
Q8N461	—	0.981	Q8N461 →