SCHEMBL10035141

SCHEMBL10035141

Cc1ccc(-c2ccc(C3CCC(C)CC3)c(F)c2F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.33
NOTUM Q6P988 1/20 0.32
ALOX5AP P20292 11/20 0.31
FEN1 P39748 11/20 0.31
HTR2C P28335 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16922998 1.00 ESR2 (0.33) ESR2NOTUMALOX5APFEN1HTR2C
SCHEMBL15834707 1.00 ESR2 (0.33) ESR2NOTUMALOX5APFEN1HTR2C
SCHEMBL12205179 0.95 ESR2 (0.31) ESR2NOTUM
SCHEMBL802760 0.93 ESR2 (0.37) ESR2NOTUMHTR2COPRL1
SCHEMBL31026 0.93 ESR2 (0.37) ESR2NOTUMHTR2COPRL1
SCHEMBL12999857 0.92 ALOX5AP (0.35) ESR2NOTUMALOX5APFEN1
SCHEMBL19754822 0.91 ESR2 (0.38) ESR2NOTUMALOX5APFEN1
SCHEMBL172422 0.91 ESR2 (0.38) ESR2NOTUMALOX5APFEN1
SCHEMBL12437063 0.91 ESR2 (0.38) ESR2NOTUMALOX5APFEN1
SCHEMBL13000001 0.88 ALOX5AP (0.33) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
US-11827829-B2 Liquid crystal composition containing dibenzo derivative and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-11-28 US disclosed
US-11788010-B2 Liquid crystal composition and liquid crystal display device comprising the same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-17 US disclosed
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-11739266-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-08-29 US disclosed
US-20230257654-A1 LIQUID CRYSTAL COMPOSITION CONTAINING DIBENZO DERIVATIVES AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-08-17 US disclosed
US-20230242817-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POYLMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-08-03 US disclosed
US-11685863-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-06-27 US disclosed
US-20230183571-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-06-15 US disclosed
US-20230159825-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-8940375-B2 Liquid-crystal display MERCK PATENT GMBH (DE) 2015-01-27 US disclosed
US-20140375943-A1 POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2014-12-25 US disclosed
US-20140139786-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
US-8114310-B2 Liquid-crystal display MERCK PATENT GMBH (DE) 2012-02-14 US disclosed
US-20100188618-A1 LIQUID-CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2010-07-29 US disclosed
US-7731865-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2010-06-08 US disclosed
US-20090324853-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-12-31 US disclosed
US-7553523-B2 Liquid crystal medium MERCK PATENT GMBH (DE) 2009-06-30 US disclosed
US-20090103011-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GESELLSCHAFT (DE) 2009-04-23 US disclosed
US-20070170395-A1 Liquid crystal medium MERCK PATENT GESELLSCHAFT 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685863-B2 Polymerisable compounds and the use thereof in liquid-crystal displays LPXN, VCL, LCP1 ESR2 2906/4885NOTUM 3611/4885ALOX5AP 1418/4885
US-20100188618-A1 LIQUID-CRYSTAL DISPLAY KLK3, LPXN, PSAP ESR2 3879/4885NOTUM 3289/4885ALOX5AP 2388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.