SCHEMBL802760

SCHEMBL802760

Cc1ccc(C2CCC(C)CC2)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.37
NOTUM Q6P988 1/20 0.35
HTR2C P28335 4/20 0.33
OPRL1 P41146 4/20 0.33
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31026 1.00 ESR2 (0.37) ESR2NOTUMHTR2COPRL1HPGD
SCHEMBL172451 0.95 ESR2 (0.34) ESR2NOTUMHTR2COPRL1
SCHEMBL15834707 0.93 ESR2 (0.33) ESR2NOTUMHTR2COPRL1
SCHEMBL16922998 0.93 ESR2 (0.33) ESR2NOTUMHTR2COPRL1
SCHEMBL10035141 0.93 ESR2 (0.33) ESR2NOTUMHTR2COPRL1
SCHEMBL19984707 0.92 NOTUM (0.38) NOTUMHTR2COPRL1HPGD
SCHEMBL21915666 0.92 NOTUM (0.38) NOTUMHTR2COPRL1HPGD
SCHEMBL12719836 0.90 ESR2 (0.43) ESR2NOTUMHTR2COPRL1
SCHEMBL12999857 0.89 ALOX5AP (0.35) ESR2NOTUM
SCHEMBL12205179 0.89 ESR2 (0.31) ESR2NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
WO-2024017812-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-01-25 WO disclosed
US-20240026223-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-01-25 US disclosed
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
US-11873438-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-7371437-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-05-13 US disclosed
US-7371437-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-05-13 US disclosed
US-20080090026-A1 Liquid-crystal display MERCK PATENT GMBH 2008-04-17 US disclosed
US-7351453-B2 Mixture of polar compounds of biphenyls, cyclohexane and phenyl substituted biphenyl; fast response time, a low threshold voltage, low temperature stability MERCK PATENT GMBH (DE) 2008-04-01 US disclosed
US-7335403-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-02-26 US disclosed
US-7326447-B2 Benzochromene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-02-05 US disclosed
WO-2008009417-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2008-01-24 WO disclosed
US-7303791-B2 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices MERCK PATENT GMBH (DE) 2007-12-04 US disclosed
US-20070080324-A1 mixture of polar compounds of negative dielectric anisotropy; electro-optical display with active-matrix addressing based on the ECB(electrically controlled birefringence), PALC (positive charge assisted leakage current) or IPS ( in plane switching) effect MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070051920-A1 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090026-A1 Liquid-crystal display KLK3, LPXN, BPHL ESR2 3823/4885NOTUM 2233/4885HTR2C 1738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.