SCHEMBL10035618

SCHEMBL10035618

Clc1c2c(nc3c1ccc1c(Cl)c4c(nc13)CCCC4)CCCC2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
ACHE P22303 15/20 0.51
BCHE P06276 9/20 0.47
CHRM1 P11229 2/20 0.47
EPHX2 P34913 1/20 0.47
GRIN1 Q05586 5/20 0.46
GRIN2A Q12879 5/20 0.46
ALDH1A1 P00352 3/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.45
CHRNE Q04844 2/20 0.44
TSHR P16473 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CACNB4 O00305 1/20 0.43
CACNA1A O00555 1/20 0.43
SLC22A2 O15244 1/20 0.43
SLC22A1 O15245 1/20 0.43
ABCC4 O15439 1/20 0.43
CACNA1G O43497 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4266767 0.77 ACHE (0.74) MAPTACHEBCHECHRM1EPHX2
SCHEMBL30658921 0.77 ACHE (0.49) MAPTACHEBCHEGRIN1GRIN2A
SCHEMBL2227659 0.77 ACHE (0.49) MAPTACHEBCHECHRM1GRIN1
SCHEMBL30991441 0.76 ACHE (0.70) MAPTACHEBCHECHRM1GRIN1
SCHEMBL1337681 0.76 ACHE (0.70) MAPTACHEBCHECHRM1GRIN1
SCHEMBL12043422 0.75 ACHE (0.68) ACHEBCHECHRM1EPHX2GRIN1
SCHEMBL3884942 0.75 ACHE (0.56) MAPTACHEBCHECHRM1EPHX2
Hydrochloric Acid SCHEMBL10404004 0.74 ACHE (0.71) MAPTACHEBCHECHRM1GRIN1
SCHEMBL31474710 0.74 BCHE (0.71) MAPTACHEBCHECHRM1GRIN1
SCHEMBL28407950 0.74 ACHE (0.68) MAPTACHEBCHECHRM1GRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2595997-B1 COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2015-09-16 EP disclosed
US-9024026-B2 Copper (I) complexes for optoelectronic devices CYNORA GMBH (DE) 2015-05-05 US disclosed
US-9024026-B2 Copper (I) complexes for optoelectronic devices CYNORA GMBH (DE) 2015-05-05 US disclosed
US-20130150581-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2013-06-13 US disclosed
US-20130150581-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2013-06-13 US disclosed
WO-2012010650-A1 COPPER (I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2012-01-26 WO disclosed