Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 11/20 | 0.62 |
| ▸ | FASN | P49327 | 2/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.46 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.46 |
| ▸ | PSMD11 | O00231 | 2/20 | 0.46 |
| ▸ | PSMD12 | O00232 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.46 |
| ▸ | PSMD3 | O43242 | 2/20 | 0.46 |
| ▸ | PSMC3 | P17980 | 2/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231027 | 1.00 | PSMB5 (0.62) | PSMB5FASNPSMB1PSMB2PSMB11 | |
| SCHEMBL10035734 | 1.00 | PSMB5 (0.62) | PSMB5FASNPSMB1PSMB2PSMB11 | |
| SCHEMBL8232847 | 1.00 | PSMB5 (0.62) | PSMB5FASNPSMB1PSMB2PSMB11 | |
| SCHEMBL10035731 | 0.94 | PSMB5 (0.70) | PSMB5FASNPSMB1PSMB2CTSL | |
| SCHEMBL8231642 | 0.94 | PSMB5 (0.70) | PSMB5FASNPSMB1PSMB2CTSL | |
| SCHEMBL8234600 | 0.94 | PSMB5 (0.70) | PSMB5FASNPSMB1PSMB2CTSL | |
| SCHEMBL10035730 | 0.94 | PSMB5 (0.70) | PSMB5FASNPSMB1PSMB2CTSL | |
| SCHEMBL10067254 | 0.90 | PSMB5 (0.56) | PSMB5FASNPSMB1PSMB2PSMB11 | |
| SCHEMBL10067250 | 0.90 | PSMB5 (0.56) | PSMB5FASNPSMB1PSMB2PSMB11 | |
| SCHEMBL8230653 | 0.89 | PSMB5 (0.53) | PSMB5FASNPSMB1PSMB2PSMB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119653-B2 | Belactosin derivatives as therapeutic agents/biological probes and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090042922-A1 | NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042922-A1 | NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS | PSMB1, PSMB10, PBK | PSMB5 23/4885FASN 2739/4885PSMB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.