SCHEMBL10035798

SCHEMBL10035798

Fc1ccc(-n2ccnc2-c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 1/20 0.51
MAPK10 P53779 1/20 0.51
KDR P35968 9/20 0.47
P2RX4 Q99571 1/20 0.43
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
GRM1 Q13255 1/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
EGFR P00533 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28821795 0.93 MAPK9 (0.46) MAPK9MAPK10KDRLMNAGAA
SCHEMBL2049367 0.93 MAPK9 (0.48) MAPK9MAPK10KDRLMNAGAA
SCHEMBL528245 0.87 MAPK9 (0.54) MAPK9MAPK10KDRP2RX4SMN1; SMN2
Benzene SCHEMBL27839441 0.87 MAPK9 (0.54) MAPK9MAPK10KDRP2RX4SMN1; SMN2
Hydrochloric Acid SCHEMBL27683877 0.85 MAPK9 (0.53) MAPK9MAPK10KDRP2RX4SMN1; SMN2
SCHEMBL5791933 0.85 EGFR (0.45) MAPK9MAPK10KDRLMNAGAA
SCHEMBL1052342 0.85 EGFR (0.45) MAPK9MAPK10KDRLMNAGAA
SCHEMBL26562756 0.84 KDR (0.55) MAPK9MAPK10KDRP2RX4LMNA
SCHEMBL28855220 0.83 MAPK9 (0.51) MAPK9MAPK10KDREGFR
SCHEMBL20918400 0.83 MAPK9 (0.51) MAPK9MAPK10KDRP2RX4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9263684-B2 Organic electroluminescent element, display device and lighting device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9263684-B2 Organic electroluminescent element, display device and lighting device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20150005504-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2015-01-01 US disclosed
US-20150005504-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2015-01-01 US disclosed
US-8404364-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2013-03-26 US disclosed
US-8404364-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2013-03-26 US disclosed
US-20120053351-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-03-01 US disclosed
US-20120053351-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-03-01 US disclosed
US-8114532-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-14 US disclosed
US-8114532-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-14 US disclosed
US-20090243479-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-10-01 US disclosed
US-20090243479-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090243479-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE L1CAM, OR51E2, TYR MAPK9 3721/4885MAPK10 3036/4885KDR 451/4885
US-20120053351-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE L1CAM, OR51E2, TYR MAPK9 3667/4885MAPK10 3055/4885KDR 416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.