SCHEMBL528245

SCHEMBL528245

c1ccc(-c2nccn2-c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 1/20 0.54
MAPK10 P53779 1/20 0.54
KDR P35968 14/20 0.52
CYP3A4 P08684 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ESR1 P03372 1/20 0.45
FLT1 P17948 1/20 0.44
FLT4 P35916 1/20 0.44
P2RX4 Q99571 1/20 0.44
CYP2E1 P05181 1/20 0.43
CYP2A6 P11509 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27839441 1.00 MAPK9 (0.54) MAPK9MAPK10KDRCYP3A4CYP1A2
Hydrochloric Acid SCHEMBL27683877 0.98 MAPK9 (0.53) MAPK9MAPK10KDRCYP3A4CYP1A2
SCHEMBL5698561 0.90 MAPK9 (0.62) MAPK9MAPK10KDRESR1FLT1
SCHEMBL29040464 0.90 MAPK9 (0.53) MAPK9MAPK10KDRCYP3A4CYP1A2
SCHEMBL11091622 0.89 KDR (0.51) MAPK9MAPK10KDRCYP3A4CYP1A2
SCHEMBL26562756 0.89 KDR (0.55) MAPK9MAPK10KDRSMN1; SMN2FLT1
SCHEMBL18999436 0.88 MAPK9 (0.46) MAPK9MAPK10KDRCYP3A4CYP1A2
Biphenyl SCHEMBL28821795 0.88 MAPK9 (0.46) MAPK9MAPK10KDRSMN1; SMN2
SCHEMBL22237823 0.87 MAPK9 (0.48) MAPK9MAPK10KDRCYP3A4CYP1A2
SCHEMBL20918400 0.87 MAPK9 (0.51) MAPK9MAPK10KDRCYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637541-B2 Alkylene oxide polymerization using aluminum compounds and cyclic amidines DOW GLOBAL TECHNOLOGIES LLC (US) 2026-05-26 US claimed
CN-117023596-B Preparation method of high-dispersibility white carbon black 河南省氟基新材料科技有限公司 2024-12-06 CN claimed
US-20240222331-A1 SEMICONDUCTOR PACKAGE AND METHOD FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-04 US claimed
CN-117644315-A High-activity post-welding low-residue tin-bismuth-silver lead-free solder paste and preparation method thereof 青岛融合装备科技有限公司 2024-03-05 CN claimed
CN-115449184-B Low-warpage thermosetting epoxy resin composite material and preparation method and application thereof 江苏中科科化新材料股份有限公司 2024-02-20 CN claimed
CN-117551410-A Non-conductive adhesive, preparation method and application thereof, flexible wearable device and preparation method thereof 深圳先进电子材料国际创新研究院 2024-02-13 CN claimed
CN-117525395-A Asphalt-based hard carbon composite material for sodium ion battery and preparation method thereof 梧州市同创循环科技有限公司 2024-02-06 CN claimed
CN-117023596-A Preparation method of high-dispersibility white carbon black 河南省氟基新材料科技有限公司 2023-11-10 CN claimed
EP-4097168-B1 ALKYLENE OXIDE POLYMERIZATION USING ALUMINUM COMPOUNDS AND CYCLIC AMIDINES DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-25 EP claimed
CN-116769281-A Preparation method of multi-load epoxy resin composite material 上海交通大学绍兴新能源与分子工程研究院 2023-09-19 CN claimed
WO-2003044089-A1 THERMOSETTING RESIN COMPOSITIONS USEFUL AS UNDERFILL SEALANTS HENKEL CORPORATION (US) 2003-05-30 WO claimed
US-6383471-B1 DRUG DELIVERY LIPOCINE, INC. 2002-05-07 US claimed
EP-1165048-A1 COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF IONIZABLE HYDROPHOBIC THERAPEUTIC AGENTS Lipocine, Inc. (US) 2002-01-02 EP claimed
US-6265412-B1 MIXTURE WITH ANTIHISTAMINE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2001-07-24 US claimed
CN-1303302-A Minoxidil-containing composition for external use TAISHO PHARMACEUTICAL CO LTD (JP) 2001-07-11 CN claimed
EP-1080730-A1 MINOXIDIL COMPOSITIONS FOR EXTERNAL USE TAISHO PHARMACEUTICAL CO., LTD (JP) 2001-03-07 EP claimed
WO-2000059475-A1 COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF IONIZABLE HYDROPHOBIC THERAPEUTIC AGENTS LIPOCINE, INC. (US) 2000-10-12 WO claimed
US-5288503-A WATER-PERMEABLE DIFFUSION BARRIER OF POLYVINYL ALCOHOL SRCHEM INCORPORATED (US) 1994-02-22 US claimed
US-5260066-A Cryogel bandage containing therapeutic agent SRCHEM INCORPORATED (US) 1993-11-09 US claimed
US-4788284-A CYAN DYES FOR PHOTOGRAPHY, PRINTING KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637541-B2 Alkylene oxide polymerization using aluminum compounds and cyclic amidines MLST8, PFAS, SQLE MAPK9 3207/4885MAPK10 3567/4885KDR 2447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.