Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | GALK1 | P51570 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689513 | 1.00 | KMT2A (0.59) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL11689520 | 1.00 | KMT2A (0.59) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL11717425 | 0.86 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL11717419 | 0.81 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL14027240 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL10870576 | 0.78 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL10870583 | 0.78 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL10878111 | 0.76 | KMT2A (0.67) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL14138728 | 0.76 | KMT2A (0.67) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL13716219 | 0.76 | KMT2A (0.67) | KMT2AMEN1ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | SNCA, PSEN1, CDR2 | KMT2A 2624/4885MEN1 2218/4885ALDH1A1 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.