Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 6/20 | 0.76 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | HTT | P42858 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALPG | P10696 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10449113 | 0.89 | PRMT1 (0.62) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL10819530 | 0.88 | PRMT1 (0.66) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL10035991 | 0.88 | PRMT1 (0.73) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL13222318 | 0.88 | PRMT1 (0.73) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL16867335 | 0.88 | PRMT1 (0.73) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| Iodide SCHEMBL7908601 | 0.87 | PRMT1 (0.73) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL10036054 | 0.86 | PRMT1 (0.83) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL12311445 | 0.86 | PRMT1 (0.83) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL14509025 | 0.86 | PRMT1 (0.69) | PRMT1PRMT5CARM1PRMT8MEN1 | |
| SCHEMBL10035967 | 0.86 | PRMT1 (1.00) | PRMT1PRMT5CARM1PRMT8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | SNCA, PSEN1, CDR2 | PRMT1 130/4885PRMT5 584/4885CARM1 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.