Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 8/20 | 0.73 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.66 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.66 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ITGAM | P11215 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867335 | 0.99 | PRMT1 (0.73) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| SCHEMBL10035991 | 0.99 | PRMT1 (0.73) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| SCHEMBL13222318 | 0.99 | PRMT1 (0.73) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| Iodide SCHEMBL7696840 | 0.96 | PRMT1 (0.69) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| Iodide SCHEMBL7696837 | 0.96 | PRMT1 (0.69) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| SCHEMBL10036128 | 0.95 | PRMT1 (0.69) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| SCHEMBL14509025 | 0.95 | PRMT1 (0.69) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| SCHEMBL10036044 | 0.87 | PRMT1 (0.76) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| Iodide SCHEMBL11688951 | 0.85 | MEN1 (0.70) | PRMT1PRMT5CARM1PRMT8NPC1 | |
| SCHEMBL13954286 | 0.84 | PRMT1 (0.65) | PRMT1PRMT5CARM1PRMT8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6181668-B1 | Optical pickup device and wavelength selective diffraction grating | SANYO ELECTRIC CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0932145-A1 | OPTICAL PICKUP DEVICE AND WAVELENGTH SELECTIVE DIFFRACTION GRATING | SANYO ELECTRIC Co., Ltd. (JP) | 1999-07-28 | — | — | EP | disclosed |