Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 16/20 | 0.87 |
| ▸ | MAPT | P10636 | 14/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.87 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.87 |
| ▸ | THRB | P10828 | 3/20 | 0.87 |
| ▸ | LMNA | P02545 | 1/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.83 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.83 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CRHBP | P24387 | 2/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.54 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.54 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.54 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022919 | 1.00 | MEN1 (0.87) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL30767820 | 1.00 | MEN1 (0.87) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL7022922 | 1.00 | MEN1 (0.87) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL11688292 | 0.93 | MEN1 (0.76) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL10036009 | 0.93 | MEN1 (0.76) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL11688300 | 0.93 | MEN1 (0.76) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL13345430 | 0.92 | MEN1 (0.78) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL10036091 | 0.91 | MEN1 (0.77) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL10331919 | 0.90 | MEN1 (0.79) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL14301214 | 0.90 | MEN1 (0.79) | MEN1KMT2AMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | SNCA, PSEN1, CDR2 | MEN1 2218/4885KMT2A 2624/4885MAPT 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.