Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.53 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607857 | 1.00 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL8358074 | 0.88 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL14848959 | 0.82 | ALDH1A1 (0.59) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL13751809 | 0.82 | ALDH1A1 (0.59) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL22906177 | 0.81 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL10036037 | 0.81 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL9194239 | 0.80 | MEN1 (0.83) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL10036014 | 0.80 | MEN1 (0.83) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL9194237 | 0.80 | MEN1 (0.83) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL10036043 | 0.79 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | SNCA, PSEN1, CDR2 | MEN1 2218/4885KMT2A 2624/4885MAPT 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.