Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.83 |
| ▸ | RAB9A | P51151 | 7/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.83 |
| ▸ | MEN1 | O00255 | 5/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.83 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.83 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | INSR | P06213 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11691452 | 1.00 | MAPT (0.83) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL2394869 | 0.91 | RAB9A (1.00) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL1348643 | 0.91 | RAB9A (1.00) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL6818840 | 0.85 | RAB9A (0.86) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL714135 | 0.82 | RAB9A (0.79) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL714134 | 0.82 | RAB9A (0.79) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL23751546 | 0.81 | MAPT (0.56) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL10435351 | 0.78 | APP (0.61) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL5945801 | 0.78 | APP (0.57) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL5945803 | 0.78 | APP (0.57) | MAPTRAB9AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | SNCA, PSEN1, CDR2 | MAPT 43/4885RAB9A 1423/4885KDM4E 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.