Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 3/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | YWHAG | P61981 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707073 | 0.89 | ALDH1A1 (0.59) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL10036398 | 0.89 | ALDH1A1 (0.59) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL3251853 | 0.86 | MAPT (0.57) | MAPTALDH1A1GAAMEN1THRB | |
| Hydrochloric Acid SCHEMBL5401575 | 0.85 | MAPT (0.59) | MAPTALDH1A1GAAMEN1THRB | |
| Hydrochloric Acid SCHEMBL27584959 | 0.85 | MAPT (0.59) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL188448 | 0.83 | MAPT (0.65) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL10036363 | 0.82 | MAPT (0.46) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL5386929 | 0.81 | MAPT (0.58) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL10126801 | 0.81 | ALDH1A1 (0.58) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL6712251 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1GAAMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |