Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.82 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.82 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.82 |
| ▸ | TNNC1 | P63316 | 6/20 | 0.82 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.82 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.82 |
| ▸ | GPR183 | P32249 | 1/20 | 0.82 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.82 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.70 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.70 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286791 | 1.00 | S1PR1 (0.82) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Hydrochloric Acid SCHEMBL7713960 | 0.98 | S1PR1 (0.83) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL3389578 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL18904548 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL1372656 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL3390328 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL3392313 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL3393539 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Fingolimod SCHEMBL7445 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL3394797 | 0.91 | S1PR1 (1.00) | S1PR1S1PR3S1PR4TNNC1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159870-A9 | METHODS AND COMPOUNDS FOR THE PREPARATION OF FLUORINE-LABELED DEOXY-FTY720 | BRACCO IMAGING S.P.A. (IT) | 2012-04-12 | — | — | WO | disclosed |
| WO-2011159870-A1 | METHODS AND COMPOUNDS FOR THE PREPARATION OF FLUORINE-LABELED DEOXY-FTY720 | BRACCO IMAGING S.P.A. (IT) | 2011-12-22 | — | — | WO | disclosed |