SCHEMBL10036725

SCHEMBL10036725

COC(=O)C1=CC=C(C(=O)Cl)CC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.44
CHRM3 P20309 2/20 0.39
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
THRB P10828 1/20 0.38
CHRM1 P11229 1/20 0.38
SLC6A3 Q01959 8/20 0.38
BLM P54132 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
SLC6A2 P23975 4/20 0.37
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35
CA2 P00918 1/20 0.35
TSHR P16473 1/20 0.34
ABL1 P00519 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5906945 0.89 PTPN1 (0.50) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL12905841 0.81 PTPN1 (0.45) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL14614628 0.79 PTPN1 (0.44) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL6858231 0.79 PTPN1 (0.55) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL12166924 0.78 PTPN1 (0.43) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL6013435 0.78 PTPN1 (0.43) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL13351646 0.78
SCHEMBL14156021 0.75 CHRM3 (0.39) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL20327874 0.75 PTPN1 (0.41) PTPN1CHRM3LMNACHRM2CHRM4
SCHEMBL20047555 0.75 PTPN1 (0.41) PTPN1CHRM3LMNACHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163205-B2 Durable transparent conductors on polymeric substrates THE BOEING COMPANY (US) 2012-04-24 US disclosed
US-20100038601-A1 DURABLE TRANSPARENT CONDUCTORS ON POLYMERIC SUBSTRATES THE BOEING COMPANY 2010-02-18 US disclosed
EP-2154689-A2 Durable transparent conductors on polymeric substrates THE BOEING COMPANY (US) 2010-02-17 EP disclosed