Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906945 | 0.87 | PTPN1 (0.50) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL19240781 | 0.82 | CA1 (0.34) | LMNABLMCA1CA2KDM4E | |
| SCHEMBL13256241 | 0.80 | PARP10 (0.35) | CA1CA2KDM4EALDH1A1GAA | |
| SCHEMBL13351646 | 0.80 | — | — | |
| SCHEMBL12905841 | 0.79 | PTPN1 (0.45) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL23188709 | 0.78 | CYP4A11 (0.37) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL10036725 | 0.78 | PTPN1 (0.44) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL14614628 | 0.78 | PTPN1 (0.44) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL6858231 | 0.78 | PTPN1 (0.55) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL12166924 | 0.76 | PTPN1 (0.43) | PTPN1CHRM3LMNACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150210900-A1 | Adhesive Material for bonding of glass to glass | AL-SHUKRI SALAH MAHDI MAJEED (IQ) | 2015-07-30 | — | — | US | disclosed |
| EP-1638961-A1 | HETEROCYCLIC SUBSTITUTED 4-(AMINOMETHYL)-PIPERIDINE BENZAMIDES AS 5HT4-ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003124-A1 | HETEROCYCLIC SUBSTITUTED 4-(AMINOMETHYL)-PIPERIDINE BENZAMIDES AS 5HT4-ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-13 | — | — | WO | disclosed |