Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 6/20 | 0.50 |
| ▸ | KYAT3 | Q6YP21 | 3/20 | 0.50 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036789 | 1.00 | AADAT (0.50) | AADATKYAT3KYAT1ABL1PRKAB2 | |
| SCHEMBL10036790 | 1.00 | AADAT (0.50) | AADATKYAT3KYAT1ABL1PRKAB2 | |
| SCHEMBL9108631 | 0.87 | AADAT (0.68) | AADATKYAT3KYAT1ABL1 | |
| SCHEMBL9108404 | 0.87 | AADAT (0.68) | AADATKYAT3KYAT1ABL1 | |
| SCHEMBL9886178 | 0.87 | AADAT (0.68) | AADATKYAT3KYAT1ABL1 | |
| SCHEMBL9886291 | 0.85 | AADAT (0.47) | AADATKYAT3KYAT1ABL1PRKAB2 | |
| SCHEMBL10067493 | 0.84 | AADAT (0.46) | AADATKYAT3KYAT1ABL1PRKAB2 | |
| SCHEMBL9236537 | 0.84 | AADAT (0.46) | AADATKYAT3KYAT1ABL1PRKAB2 | |
| SCHEMBL10036788 | 0.82 | AADAT (0.53) | AADATKYAT3KYAT1ACHE | |
| SCHEMBL10036777 | 0.82 | AADAT (0.53) | AADATKYAT3KYAT1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487104-B2 | KAT II inhibitors | PFIZER INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20120142729-A1 | KAT ll INHIBITORS | PFIZER INC. | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142729-A1 | KAT ll INHIBITORS | KAT7, KAT2A, KATNA1 | AADAT 1043/4885KYAT3 90/4885KYAT1 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.