Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17221758 | 0.73 | MEN1 (0.43) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL28662503 | 0.70 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL17221757 | 0.70 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL9055148 | 0.69 | MAPT (0.52) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL8365427 | 0.68 | ALDH1A1 (0.58) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13750887 | 0.67 | TACR1 (0.40) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL17072650 | 0.66 | MEN1 (0.53) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL10287951 | 0.63 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL86112 | 0.63 | KMT2A (0.48) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL29007581 | 0.63 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187523-B2 | Substrate peptide sequences for plague plasminogen activator and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-11-17 | — | — | US | disclosed |
| US-20120045474-A1 | Substrate peptide sequences for plague plasminogen activator and uses thereof | MOTIN VLADIMIR L (US) | 2012-02-23 | — | — | US | disclosed |
| US-8030447-B2 | Substrate peptide sequences for plague plasminogen activator and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-10-04 | — | — | US | disclosed |
| US-20090069248-A1 | Substrate peptide sequences for plague plasminogen activator and uses thereof | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, THE | 2009-03-12 | — | — | US | disclosed |