Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609709 | 0.80 | PTPN2 (0.64) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL5103381 | 0.79 | ABCC1 (0.63) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL28804997 | 0.79 | PTPN2 (0.62) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL7821857 | 0.79 | PTPN2 (0.62) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL2255525 | 0.78 | ABCC1 (0.57) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL4958864 | 0.77 | ABCC1 (0.60) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL1704250 | 0.76 | PTPN2 (0.68) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL23931980 | 0.76 | PTPN2 (0.72) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL429230 | 0.75 | PTPN2 (0.57) | ABCC1PTPN2PTPN1MEN1KMT2A | |
| SCHEMBL14231553 | 0.75 | ABCC1 (0.57) | ABCC1PTPN2PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | ABCC1 852/4885PTPN2 2234/4885PTPN1 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.