SCHEMBL10039288

SCHEMBL10039288

FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(c2ccc(Cl)c(NNC(=S)Nc3ccccc3)c2)=NO1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 1/20 0.34
GAA P10253 10/20 0.34
ALDH1A1 P00352 8/20 0.34
HTT P42858 5/20 0.34
MAPT P10636 4/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
LMNA P02545 4/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.34
NOD2 Q9HC29 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AGTR1 P30556 2/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
KCNJ6 P48051 1/20 0.32
KCNJ5 P48544 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10039190 0.90 KCNJ6 (0.39) GAAALDH1A1HTTMAPTLMNA
SCHEMBL1547694 0.85 KMT2A (0.38) GAAALDH1A1HTTMAPTSMN1; SMN2
SCHEMBL566693 0.84 GAA (0.36) GAAALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL565154 0.83 MAPT (0.41) GAAALDH1A1HTTMAPTSMN1; SMN2
SCHEMBL10039065 0.83 LMNA (0.39) GAAALDH1A1HTTMAPTSMN1; SMN2
SCHEMBL565155 0.83 MAPT (0.41) GAAALDH1A1HTTMAPTSMN1; SMN2
SCHEMBL565338 0.82 ORAI1 (0.39) GAAALDH1A1HTTMAPTSMN1; SMN2
SCHEMBL472622 0.82 CA1 (0.33) GAAALDH1A1HTTMAPTSMN1; SMN2
SCHEMBL472295 0.82 CA1 (0.35) GAARAB9AF10MEN1KMT2A
SCHEMBL472626 0.81 CA1 (0.32) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507514-B2 Hydrazide compound and use of the same in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-13 US disclosed
EP-2601835-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
US-20130137682-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130131118-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131083-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131117-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131115-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131116-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
WO-2012017973-A1 PEST CONTROL COMPOSITION 住友化学株式会社 (JP) 2012-02-09 WO disclosed
WO-2012017970-A1 PEST CONTROL COMPOSITION 住友化学株式会社 (JP) 2012-02-09 WO disclosed
WO-2012017971-A1 PEST CONTROL COMPOSITION 住友化学株式会社 (JP) 2012-02-09 WO disclosed
US-20120035218-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
WO-2012017969-A1 PEST CONTROL COMPOSITION 住友化学株式会社 (JP) 2012-02-09 WO disclosed
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130137682-A1 PEST CONTROL COMPOSITION H1-4, HRH4, CHRM2 NOX1 132/4885GAA 3339/4885ALDH1A1 1150/4885
US-20130131115-A1 PEST CONTROL COMPOSITION HRH2, HRH4, HRH1 NOX1 1108/4885GAA 3125/4885ALDH1A1 994/4885
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL H1-4, H1-2, H1-0 NOX1 130/4885GAA 3589/4885ALDH1A1 690/4885
US-20130131118-A1 PEST CONTROL COMPOSITION H1-4, H1-10, H1-0 NOX1 782/4885GAA 3204/4885ALDH1A1 1791/4885
US-20130131116-A1 PEST CONTROL COMPOSITION H1-4, H1-10, H1-0 NOX1 816/4885GAA 2998/4885ALDH1A1 2099/4885
US-20130131083-A1 PEST CONTROL COMPOSITION H1-4, H1-3, H1-0 NOX1 512/4885GAA 3896/4885ALDH1A1 2372/4885
US-20130131117-A1 PEST CONTROL COMPOSITION H1-4, H1-0, H1-2 NOX1 310/4885GAA 3029/4885ALDH1A1 600/4885
US-20120035218-A1 PEST CONTROL COMPOSITION CTRL, CYP4F3, CYP4B1 NOX1 422/4885GAA 3030/4885ALDH1A1 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.