Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.69 |
| ▸ | TUBB | P07437 | 4/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.69 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.69 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.69 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | P4HB | P07237 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16002088 | 0.95 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12373774 | 0.95 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18715702 | 0.95 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14922846 | 0.95 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14850589 | 0.95 | TUBB4A (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14143956 | 0.94 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25801089 | 0.94 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12673500 | 0.91 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13024629 | 0.91 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16996785 | 0.91 | TUBB4A (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119787-B2 | Molecular tools for manufacturing anti-CD33 antibodies and fragments | IMMUNOGEN, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110008840-A1 | ANTI-CD33 ANTIBODIES AND METHODS FOR TREATMENT OF ACUTE MYELOID LEUKEMIA USING THE SAME | IMMUNOGEN, INC. (US) | 2011-01-13 | — | — | US | disclosed |