TUBB4A

Tubulin beta-4A chain · P04350 · TUBB4A on Sugi Atlas →

134,687 patent compounds predicted against TUBB4A, 85,635 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Curacin A Curacin A (SCHEMBL61304) 1.00 20/20
Vintriptol Vintriptol (SCHEMBL93959) 1.00 15/20
Vindesine Vindesine (SCHEMBL4420) 0.85 13/20
Vindesine Vindesine (SCHEMBL4421) 0.85 13/20
Vindesine Vindesine (SCHEMBL4285) 0.85 12/20
SCHEMBL147173 SCHEMBL147173 0.50 12/20
SCHEMBL147174 SCHEMBL147174 0.50 12/20
Combretastatin Combretastatin (SCHEMBL19955) 1.00 9/20
Combretastatin Combretastatin (SCHEMBL19956) 1.00 9/20
SCHEMBL118593 SCHEMBL118593 0.69 9/20
Centaureidin Centaureidin (SCHEMBL9953) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43160) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43161) 1.00 8/20
SCHEMBL68067 SCHEMBL68067 0.62 8/20
Fosbretabulin Fosbretabulin (SCHEMBL66079) 0.61 8/20
Vinorelbine Vinorelbine (SCHEMBL4765) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18945) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18946) 1.00 7/20
Levofloxacin Anhydrous Levofloxacin Anhydrous (SCHEMBL15397) 0.98 7/20
Ofloxacin Ofloxacin (SCHEMBL24373) 0.98 7/20

Clinical trials — most relevant to TUBB4A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparative Analysis of the Efficacies in Neoadjuvant Chemotherapy of Breast Cancer PHASE3COMPLETED
The ECLA PHRI COLCOVID Trial. Effects of Colchicine on Moderate/High-risk Hospitalized COVID-19 Patients. PHASE3COMPLETED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Neoadjuvant Paclitaxel Plus Epirubicin Versus Vinorelbine Plus Epirubicin in Breast Cancer With TEKT4 Variations PHASE2COMPLETED
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer PHASE2COMPLETED
SB-715992 in Treating Patients With Metastatic or Recurrent Malignant Melanoma PHASE2COMPLETED
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer PHASE2UNKNOWN
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Treating Patients With Advanced Solid Tumors, Breast Cancer or Recurrent Ovarian Cancer PHASE1COMPLETED
Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia PHASE1UNKNOWN
Exploratory Evaluation of [11C]MPC6827 EARLY_PHASE1COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children nanCOMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Prostate Cancer Antigen 3 (PCA-3) Gene Project nanCOMPLETED
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting nanUNKNOWN
The Relation of Microtubule-Associated Protein 2 and Cell Migration nanUNKNOWN
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Myotubular Myopathy Genetic Testing Study nanCOMPLETED
Evaluation of a Novel PET Radioligand to Image OGA nanCOMPLETED
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury nanCOMPLETED
Evaluation of Lymph Node Analysis Using One Step Nucleic Acid Amplification (OSNA) in Patients With Lung Cancer Who Underwent Robotic Lung Resection, Comparison With Traditional Methods nanENROLLING_BY_INVITATION
Identification of Viable Human Embryos Using Three Different Methods nanCOMPLETED
KCNA3 and OTOP2 Gene Methylation Combined Detection Kit (Fluorescent PCR Method) nanCOMPLETED
WGS of Korean Idiopathic Bronchiectasis nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a TUBB4A binder may also engage these)

ProteinNameSimilarity
Q4R4X8 1.000 Q4R4X8 →
P68372 1.000 P68372 →
Q3MHM5 1.000 Q3MHM5 →
P69893 1.000 P69893 →
P11833 1.000 P11833 →
Q9D6F9 1.000 Q9D6F9 →
Q3ZBU7 1.000 Q3ZBU7 →
P46265 1.000 P46265 →
Q6GLE7 1.000 Q6GLE7 →
TUBB2A Tubulin beta-2A chain 1.000 landscape →
P85108 1.000 P85108 →
Q5R943 1.000 Q5R943 →
Q2HJ81 1.000 Q2HJ81 →
Q6B856 1.000 Q6B856 →
TUBB2B Tubulin beta-2B chain 1.000 landscape →
Q6P9T8 1.000 Q6P9T8 →
O44388 1.000 O44388 →
Q27U48 1.000 Q27U48 →
P12456 1.000 P12456 →
P69895 1.000 P69895 →
Q2KJD0 1.000 Q2KJD0 →
Q91240 1.000 Q91240 →
Q767L7 1.000 Q767L7 →
P09244 1.000 P09244 →
P99024 1.000 P99024 →
P30883 1.000 P30883 →
P69897 1.000 P69897 →
Q7JJU6 1.000 Q7JJU6 →
Q9YHC3 1.000 Q9YHC3 →
Q91575 1.000 Q91575 →