SCHEMBL10040180

SCHEMBL10040180

O=Cc1cc(C(c2ccc(C=O)c(C(=O)O)c2)(C(F)(F)F)C(F)(F)F)ccc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ USP2 O75604 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ GRIK1 P39086 2/20 0.35
▸ ESR1 P03372 1/20 0.34
▸ ESR2 Q92731 1/20 0.34
▸ SORT1 Q99523 8/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ KDM1A O60341 1/20 0.34
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ LIPC P11150 1/20 0.33
▸ LIPG Q9Y5X9 1/20 0.33
▸ CES2 O00748 2/20 0.33
▸ CFTR P13569 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78675 0.82 ALDH1A1 (0.59) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL78139 0.82 ALDH1A1 (0.54) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL109108 0.80 HSD17B10 (0.50) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL29441324 0.80 HSD17B10 (0.50) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL29401067 0.80 HSD17B10 (0.50) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL9492931 0.80 HSD17B10 (0.50) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL1770132 0.80 HSD17B10 (0.50) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL13382715 0.80 TYMS (0.39) KDM4EALDH1A1HPGDHSD17B10USP2
SCHEMBL14412566 0.80 CA12 (0.38) KDM4EALDH1A1HPGDHSD17B10GRIK1
SCHEMBL10000034 0.79 ESR1 (0.34) KDM4EALDH1A1HPGDHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10679660-B2 Magnetic tape and magnetic tape device FUJIFILM CORPORATION (JP) 2020-06-09 — — US disclosed
US-10477072-B2 Magnetic tape having characterized magnetic layer and hexagonal ferrite powder FUJIFILM CORPORATION (JP) 2019-11-12 — — US disclosed
US-20190295590-A1 MAGNETIC TAPE AND MAGNETIC TAPE DEVICE FUJIFILM CORPORATION (JP) 2019-09-26 — — US disclosed
US-9984711-B2 Magnetic recording medium and coating composition for magnetic recording medium FUJIFILM CORPORATION (JP) 2018-05-29 — — US disclosed
US-20180061446-A1 MAGNETIC TAPE FUJIFILM CORPORATION (JP) 2018-03-01 — — US disclosed
US-20170355022-A1 MAGNETIC TAPE AND MAGNETIC TAPE DEVICE FUJIFILM CORPORATION (JP) 2017-12-14 — — US disclosed
US-8337586-B2 Crosslinked polyimide membrane, method for making the same using organic titanate catalysts to facilitate crosslinking and method of using the membrane for fluid separation CHEVRON U.S.A. INC. (US) 2012-12-25 — — US disclosed
US-20120241996-A1 CROSSLINKED POLYIMIDE MEMBRANE, METHOD FOR MAKING THE SAME USING ORGANIC TITANATE CATALYSTS TO FACILITATE CROSSLINKING AND METHOD OF USING THE MEMBRANE FOR FLUID SEPARATION CHEVRON U.S.A. INC. (US) 2012-09-27 — — US disclosed
US-20120048107-A1 METHODS OF PREPARING A CROSSLINKED FIBER MEMBRANE CHEVRON U.S.A. INC. 2012-03-01 — — US disclosed
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